Primary angle-closure glaucoma (PACG) affects nearly 17 million people worldwide. A shallow anterior chamber and a short axial length increase the risk of angle closure and development of glaucomatous neuropathy. The progress of PACG is also associated with genetic predisposition. A 48-year-old female patient presented to the Outpatient Ophthalmology Clinic. Her sister had undergone two central decompressing vitrectomies due to advanced PACG. The patient was referred for additional examinations: tonometry, anterior segment optical coherence tomography (AS-OCT), gonioscopy, and static perimetry. The patient was qualified for prophylactic laser peripheral iridotomy (LPI) in both eyes. AS-OCT and gonioscopy revealed a closed angle in the right eye (oculus dexter – OD), a slit-like angle in the left eye (oculus sinister – OS), and a shallow anterior chamber in both eyes. The intraocular pressure (IOP) was measured at 20 mmHg in the OD and 15 mmHg in the OS. A peripheral relative visual field defect was found in the OD. Follow-up tonometry performed 14 months after the initial LPI showed an IOP of 27 mmHg in the OD. Timolol 0.5% was prescribed. Despite this, after 3 months, the IOP in the OD measured 22 mmHg. The patient was qualified for a repeat LPI in the OD. At follow-up, the IOP was 21 mmHg in the OD. Visual acuity was 1.0 in both eyes. LPI is the first-line treatment for PACG. Even though this procedure is highly effective, it does not guarantee long-term results. In case of recurrence, qualification for anti-glaucoma surgical intervention should be considered.