Clinical applications of the Laser-assisted Optical Rotational Cell Analyser LORCA

Ludmiła Słowińska; Karol Monkos

3-4/2010 vol. 64

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Clinical applications of the Laser-assisted Optical Rotational Cell Analyser LORCA

Ludmiła Słowińska ¹

Karol Monkos

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Department of Biophysics, Medical University of Silesia, H. Jordana 19, 41-808 Zabrze 8, Poland

Corresponding author

Karol Monkos

Zakład Biofizyki Śląski Uniwersytet Medyczny, ul. H. Jordana 19, 41-808 Zabrze 8, tel. +48 32 272 20 41/236 fax +48 32 272 01 42

Ann. Acad. Med. Siles. 2010;64:42-47

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References (12)

KEYWORDS

erythrocytes

deformability

aggregation amplitude

aggregation index

elongation index

ABSTRACT

Laser-assisted Optical Rotational Cell Analyser LORCA is a precise instrument capable to investigation of aggregations and deformability of erythrocytes. In the paper the action principles of the instruments is presented and the measured quantities such as the aggregation amplitude, aggregation half time, aggregation index and elongation index are defined. A comparison of mean values of those quantities for the control group and groups of patients with obesity (body mass index – BMI > 35), pancreas tumor, myocardial infarction, obstructive sleep apnea, age-related macular degeneration and diabetes mellitus of the type 2 is made.

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