The use of dietary supplements supporting functioning of musculoskeletal system in rehabilitation clinic patients
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Koło Naukowe przy Katedrze Zdrowia Środowiskowego, Wydział Nauk o Zdrowiu w Bytomiu, Śląski Uniwersytet Medyczny w Katowicach
Zakład Zdrowia Środowiskowego, Wydział Nauk o Zdrowiu w Bytomiu, Śląski Uniwersytet Medyczny w Katowicach
Weronika Osmala-Kurpiewska   

Zakład Zdrowia Środowiskowego, Wydział Nauk o Zdrowiu w Bytomiu, ul. Piekarska 18, 41-902 Bytom
Ann. Acad. Med. Siles. 2022;76:80–85
Musculoskeletal conditions are often characterized by pain, as well as limited physical function. To alleviate pain accompanying musculoskeletal diseases, non-steroidal anti-inflammatory drugs (NSAIDs) and/or paracetamol are used. Dietary supplements, however, are increasingly being considered by patients with these types of conditions as additional treatment aids. The aim of the study was the quantitative and qualitative analysis of dietary supplements and the subjective assessment of patients regarding the effect of supplements on the reduction of musculoskeletal disorders.

Material and methods:
The study used the author’s own questionnaire to conduct a survey in a group of 171 patients, including 110 (64%) women and 61 (36%) men, of a rehabilitation clinic in Katowice. The survey questionnaire consisted of questions concerning, among others, the types of past injuries, the use of dietary supplements, as well as subjective feelings related to their use.

Most respondents used preparations containing collagen (30.9%) and glucosamine (30%). Most of the respondents (43.6%) chose the supplement after consulting a doctor or physiotherapist. The large majority of respondents (65.4%) observed improvement after using the dietary supplement.

The study showed that the majority of patients using dietary supplements that affect musculoskeletal function experienced improvements, most often after a month of taking them. Among the most commonly chosen dietary supplements were those that contained collagen and glucosamine in their formulation.

Briggs A.M., Woolf A.D., Dreinhöfer K., Homb N., Hoy D.G., Kopansky-Giles D. et al. Reducing the global burden of musculoskeletal conditions. Bull. World Health Organ. 2018; 96(5): 366–368, doi: 10.2471/BLT.17.204891.
Briggs A.M., Cross M.J., Hoy D.G., Sànchez-Riera L., Blyth F.M., Woolf A.D. et al. Musculoskeletal Health Conditions Represent a Global Threat to Healthy Aging: A Report for the 2015 World Health Organization World Report on Ageing and Health. Gerontologist 2016; 56 Suppl 2: S243–255, doi: 10.1093/geront/gnw002.
Jańczyk A., Sawczuk M. Selected dietary supplements for treating osteoarthritis. [Article in Polish]. Farmacja Współcz. 2019; 12: 29–35.
da Costa B.R., Reichenbach S., Keller N., Nartey L., Wandel S., Jüni P. et al. Effectiveness of non-steroidal anti-inflammatory drugs for the treatment of pain in knee and hip osteoarthritis: a network meta-analysis. Lancet 2017; 390(10090): e21–e33, doi: 10.1016/S0140-6736(17)31744-0.
Background information: dietary supplements. National Institutes of Health, 2020 [online] [accessed on August 1, 2022].
Merchut N., Reczyński W. Procedure of the human articular cartilage sample preparation for the metals’ determination by means of Atomic Absorption Spectrometry. [Article in Polish]. Analit 2019; 7: 44–50.
Czerwiński A., Liebers D. Regulacja rynku suplementów diety: czy Polska ma szansę zostać europejskim liderem? Policy Paper 9/2019. Polski Instytut Ekonomiczny. Warszawa 2019.
Noack W., Fischer M., Förster K.K., Rovati L.C., Setnikar I. Glucosamine sulfate in osteoarthritis of the knee. Osteoarthritis Cartilage 1994; 2(1): 51–59, doi: 10.1016/s1063-4584(0)80006-8.
Vasiliadis H.S., Tsikopoulos K. Glucosamine and chondroitin for the treatment of osteoarthritis. World J. Orthop. 2017; 8(1): 1–11, doi: 10.5312/wjo.v8.i1.1.
Jüni P. Alternative Treatment Options for Osteoarthritis: Facts and Evidence on Glucosamines and Chondroitin [pdf]. Fact sheet No. 8. International Association for the Study of Pain 2016. Available at: [accessed on August 1, 2022].
Marzec A., Skrzypek M., Marzec Z. Dietary supplements as a challenge for contemporary public health: scale of the phenomenon, health risk, legal regulations. Pol. J. Public Health 2018; 128(1): 30–35, doi: 10.2478/pjph-2018-0006.
Woroń J. Pharmacological treatment of osteoarthritis – current recommendations. [Article in Polish]. Lekarz POZ 2020; 6(1): 33–36.
Wordliczek J., Woroń J., Targońska-Stępniak B., Tarnacka B., Malec-Milewska M. Treatment of inflammatory pain – an interdisciplinary problem from the perspective of a rheumatologist, neurologist, physiotherapist, pain specialist and clinical pharmacologist. [Article in Polish]. Ból 2018; 19(4): 11–26, doi: 10.5604/01.3001.0013.2753.
Häuselmann H.J. Nutripharmaceuticals for osteoarthritis. Best Pract. Res. Clin. Rheumatol. 2001; 15(4): 595–607, doi: 10.1053/berh.2001.0176.
Kwatra B., Goenka M., Kumar AVP., Shenoy N.N. Therapeutic Applications of Chondroitin Sulphate, Collagen and Rosehip Extract in the Musculoskeletal System. Int. J. Innov. Sci. Res. Technol. 2020; 5(8): 825–837, doi: 10.38124/IJISRT20AUG527.
Yoshioka N.K., Young G.M., Khajuria D.K., Karuppagounder V., Pinamont W.J., Fanburg-Smith J.C. et al. Structural changes in the collagen network of joint tissues in late stages of murine OA. Sci. Rep. 2022; 12: 9159, doi: 10.1038/s41598-022-13062-y.
Kostecka M. Stosowanie suplementów diety przez osoby w wieku starszym. Bromat. Chem. Toksykol. 2015; 48(4): 758–765.
Sanders M., Grundmann O. The use of glucosamine, devil’s claw (Harpagophytum procumbens), and acupuncture as complementary and alternative treatments for osteoarthritis. Altern. Med. Rev. 2011; 16(3): 228–238.
Simental-Mendía M., Sánchez-García A., Vilchez-Cavazos F., Acosta-Olivo C.A., Peña-Martínez V.M., Simental-Mendía L.E. Effect of glucosamine and chondroitin sulfate in symptomatic knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials. Rheumatol. Int. 2018; 38(8): 1413–1428, doi: 10.1007/s00296-018-4077-2.
Biggee B.A., Blinn C.M., McAlindon T.E., Nuite M., Silbert J.E. Low levels of human serum glucosamine after ingestion of glucosamine sulphate relative to capability for peripheral effectiveness. Ann. Rheum. Dis. 2006; 65(2): 222–226, doi: 10.1136/ard.2005.036368.
Jawed H., Anjum S., Awan S.I., Simjee S.U. Anti-arthritic effect of GN1, a novel synthetic analog of glucosamine, in the collagen-induced arthritis model in rats. Inflamm. Res. 2011; 60(12): 1113–1120, doi: 10.1007/s00011-011-0375-9.
Hui J.H., Chan S.W., Li J., Goh J.C.H., Li L., Ren X.F. et al. Intra-articular delivery of chondroitin sulfate for the treatment of joint defects in rabbit model. J. Mol. Histol. 2007; 38(5): 483–489, doi: 10.1007/s10735-007-9120-7.
Sherman A.L., Ojeda-Correal G., Mena J. Use of glucosamine and chondroitin in persons with osteoarthritis. PM R 2012; 4(5 Suppl): S110–116, doi: 10.1016/j.pmrj.2012.02.021.
Vangsness C.T. Jr., Spiker W., Erickson J. A review of evidence-based medicine for glucosamine and chondroitin sulfate use in knee osteoarthritis. Arthroscopy 2009; 25(1): 86–94, doi: 10.1016/j.arthro.2008.07.020.
Bourgeois P., Chales G., Dehais J., Delcambre B., Kuntz J.L., Rozenberg S. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3 x 400 mg/day vs placebo. Osteoarthritis Cartilage 1998; 6(Suppl A): 25–30, doi: 10.1016/s1063-4584(98)80008-3.
Noack W., Fischer M., Förster K.K., Rovati L.C., Setnikar I. Glucosamine sulfate in osteoarthritis of the knee. Osteoarthritis Cartilage 1994; 2(1): 51–59, doi: 10.1016/s1063-4584(05)80006-8.
Bruyère O., Zegels B., Leonori L., Rabenda V., Janssen A., Bourges C. et al. Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo controlled study. Complement. Ther. Med. 2012; 20(3): 124–130, doi: 10.1016/j.ctim.2011.12.007.
Van Vijven J.P.J., Luijsterburg P.A.J., Verhagen A.P., van Osch G.J.V.M., Kloppenburg M., Bierma-Zeinstra S.M.A. Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review. Osteoarthritis Cartilage 2012; 20(8): 809–821, doi: 10.1016/j.joca.2012.04.008.