The share of pathogenic strains of Gram (-) along with profiles of drug resistance occurring in bacterial infections in patients hospitalized in Department of Lung Diseases and Tuberculosis in Zabrze, Medical University of Silesia in Katowice
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Katedra i Zakład Mikrobiologii i Immunologii, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Śląski Uniwersytet Medyczny w Katowicach
Katedra i Klinika Chorób Płuc i Gruźlicy, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Śląski Uniwersytet Medyczny w Katowicach
Bogdan Mazur   

Katedra i Zakład Mikrobiologii i Immunologii, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Śląski Uniwersytet Medyczny w Katowicach, ul. Jordana 19, 41-808 Zabrze
Ann. Acad. Med. Siles. 2019;73:81–88
Respiratory infections still pose a threat to human life and health. Recurrent inflammations of the respiratory tract are a very important problem because of the complex causes of their formation. In recurrent infections, many chronic diseases are diagnosed too late because of the large diversity and variability of clinical symptoms. Bacterial infections are among the causes of a number of exacerbations of obstructive respiratory diseases. In the hospital, infections of the respiratory system are dominated by Gram (-) rod-shaped bacteria Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, Acinetobacter spp. These microorganisms isolated from infections are increasingly characterized by resistance to most, and sometimes all, available drugs. The aim of the study was to assess the species of Gram (-) rod-shaped bacteria, their number and profile of drug resistance cultured from patients in the Department of Lung Diseases and Tuberculosis of the Independent Public Clinical Hospital No. 3 in Zabrze in 2008–2012.

Material and methods:
We evaluated the results of bacteriological tests of sputum and bronchial lavage obtained in the Microbiological Laboratory of the Department of Microbiology and Immunology in Zabrze, Medical University of Silesia in Katowice. In a period of 5 years, 3810 studies of bronchial lavage and sputum were conducted.

1263 strains of pathogenic bacteria were bred, including 818 strains of Gram (-) bacilli, which accounted for 64.8% of the total number of pathogenic bacteria. Gram (-) microorganisms in 2008–2012 showed the highest percentage of resistance in relation to tetracyclines, then to penicillin and penicillin with inhibitors, sulfonamides and trimethoprim, and secondarily to cephalosporins, quinolones and aminoglycosides.

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