Malondialdehyde (MDA) – product of lipid peroxidation as marker of homeostasis disorders and aging
 
More details
Hide details
1
Department of Human Nutrition, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland
 
2
Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland
 
 
Corresponding author
Katarzyna Weronika Walkiewicz   

Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland, ul. Piekarska 18, 41-902 Bytom, tel. 32 281 21 22,
 
 
Ann. Acad. Med. Siles. 2016;70:224-228
 
KEYWORDS
TOPICS
ABSTRACT
Malondialdehyde (MDA) found in the body comes from two sources: food consumed and lipid peroxidation occurring in the tissues. The formation of MDA and the scale and rate of lipid oxidation in the tissues of living organisms is influenced by a number of endo- and exogeneous factors. The products of lipid peroxidation, in particular MDA, exhibit cytotoxic, mutagenic and carcinogenic properties. They can also inhibit enzymes associated with defending cells against oxidative stress. Not only do the occurring processes contribute to the development of many diseases, but they are also a part of the aging process. The body defends itself to some extent against the effects of free radicals by trapping and neutralising them. The main source of antioxidants is food products of plant origin. Lifestyle, the components of which are diet and physical activity, is an important element in preserving health understood as physical and psychological well-being. Dietary habits and a diet rich in antioxidants are modifiable factors which not only prevent age-associated diseases, but also delay aging processes.
 
REFERENCES (44)
1.
Demography Report 2010. Older, more numerous and diverse Euro-peans, European Commission, 2011; www.healthyageing.eu/file resources/ /EUL14135_ Demographyreport_ web.pd.
 
2.
European Commission (DG ECFIN) and Economic Policy Committee (Ageing Working Group). The 2015 Ageing Report. Economic and budgetary projections for the 28 EU Member States 2013–2030. Luxembourg: Publications Office of the European Union, 2015.
 
3.
Harman D. Aging: a theory based on free radicals and radiation che-mistry. J. Gerontol. 1956; 11(3): 288–300.
 
4.
Dmitriev L.F., Titov V.N. Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases. Ageing Res. Rev. 2010; 9(2): 200–210.
 
5.
Niedworok E., Bielaszka A. Comparison of the Effect of Vitamins A and E on Aging Processes of Edible Vegetable Oils. Polish J. of Environ. Stud. 2007; 16(6): 861–865.
 
6.
Marnett L.J, Bienkowski M.J, Raban M., Tuttle M.A. Studies of the hydrolysis of14C-labeled tetraethoxypropane to malondialdehyde. Anal. Biochem. 1979; 99: 458–463.
 
7.
Valko M., Rhodes C.J., Moncol J., Izakovic M., Mazur M. Free radicals, metals and antioxidants in oxidative stress – induced cancer. Chem. Biol. Interact. 2006; 160: 1–40.
 
8.
Marnett L.J. Oxy radicals, lipid peroxidation and DNA damage. Toxicol 2002; 181–182: 219–222.
 
9.
Blair I.A. Lipid hydroperoxide-mediated DNA damage. Exp. Gerontol. 2001; 36: 1473–1481.
 
10.
Niederhofer L.J., Daniels J.S., Rouzer C.A., Greene R.E., Marnett L.J. Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells. J. Biol. Chem. 2003; 278(33): 31426–31433.
 
11.
Chen J.I., Petersen D.R., Schenker S., Henderson G.I. Formation of malondialdehyde adducts in livers of rats exposed to ethanol: role in ethanol-mediated inhibition of cytochrome c oxidase. Alcohol Clin. Exp. Res. 2000; 24(4): 544–552.
 
12.
Casado A., Encarnación López-Fernández M., Concepción Casado M., de La Torre R. Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias. Neurochem Res. 2008; 33(3): 450–458.
 
13.
Siu G.M., Draper H.H. Metabolism of malonaldehyde in vivo and in vitro. Lipids 1982; 17(5): 349–355.
 
14.
Raghavan S., Subramaniyam G., Shanmugam N. Proinflammatory effects of malondialdehyde in lymphocytes. J. Leukoc. Biol. 2012; 92(5): 1055–1067.
 
15.
Yang I.Y., Chan G., Miller H., Huang Y., Torres M.C., Johnson F., Moriya M. Mutagenesis by acrolein-derived propane deoxyguanosine adducts in human cells. Biochemistry 2002; 41: 13826–13832.
 
16.
De Bont R., Van Larebeke N. Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 2004; 19: 169–185.
 
17.
Veneskoski M., Turunen S.P., Kummu O., Nissinen A., Rnnikko S., Levonen A.L., Hörkkö S. Specific recognition of malondialdehyde and malondialdehyde acetaldehyde adducts on oxidized LDL and apoptotic cells by complement anaphylatoxin C3a. Free Radical Biol. Med. 2011; 51(4): 834–843.
 
18.
Rani V., Yadav U.C. Free radicals in Human Health and Diseases. Springer. India 2015.
 
19.
Gil L., Siems W., Mazurek B., Gross J., Schroeder P., Voss P., Grune T. Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes. Free Radic. Res. 2006; 40: 495–505.
 
20.
Suresh D.R., Sendil K., Annam V., Hamasaveena Age related changes in malondialdehyde: total antioxidant capacity ratio- a novel marker of oxidative stress. Int. J. Pharm. Bio. Sci. 2010; 1(2): 1–6.
 
21.
Jha R., Rizvi S.I. Carbonyl formation in erythrocyte membrane proteins during aging in humans. Biomed Pap. Med. Fac. Univ. Palacky Olomunc 2011; 155(1): 39–42.
 
22.
Mahla V.K., Mahla M., Gupta R.C., Rawtani J. A study to evaluate the effect of menopause on oxidative stress. International Journal of Physiology 2014; 2(1): 118–123.
 
23.
Casado A., Encarnación López-Fernández M., Concepción Casado M., de La Torre R. Lipid peroxidation and antioxidant enzyme activities in vascular and Alzheimer dementias. Neurochem. Res. 2008; 33(3): 450–458.
 
24.
Dzięgielewska-Gęsiak S., Wysocka E., Michalak S., Nowakowska-Zaj-del E., Kokot T., Muc-Wierzgoń M. Role of lipid peroxidation products, plasma total antioxidant atatus, and Cu-, Zn-superoxide dismutase activity as biomarkers of oxidative stress in elderly prediabetics. Oxid. Med. Cell. Longev 2014; 2014: ID987303, p. 1–8.
 
25.
Karolkiewicz J. Effects of oxidative stress and free-radical mediated damage on cell structure and function – connection to aging process. Ge-rontol. Pol. 2011; 19(2): 59–67.
 
26.
Klaunig J., Kamendulis L., Hocevar B. Oxidative stress and oxidative damage in carcinogenesis. Toxicol Pathol. 2010; 38(1): 96–109.
 
27.
Sosa V., Moliné T., Somoza R. Paciucci R., Kondoh H., Lleonart M.E. Oxidative stress and cancer: An overview Ageing Res. Rev. 2013; 12: 376–390.
 
28.
Parše M. Oxidative stress in the pathogenesis of colorectal cancer: cause or consequence? Biomed Res. Int. 2013; ID 725710.
 
29.
Gönenç A., Ozkan Y., Torun M., Simşek B. Plasma malondialdehyde (MDA) levels in breast and lung cancer patients. J. Clin. Pharm. Therap. 2001; 26(2): 141–144.
 
30.
Aznar J., Santos M.T., Valles J., Sala J. Serum malondialdehyde-like material (MDA-LM) in acute myocardial infarction. J. Clin. Pathol. 1983; 36: 712–715.
 
31.
Lee R., Margaritis N., Channon K.M., Antoniades C. Evaluating Oxidative Stress in Human Cardiovascular Disease: Methodological Aspects and Considerations. Curr. Med. Chem. 2012; 19(16): 2504–2520.
 
32.
Antoniades C., Antonopoulos A.S., Bendall J.K., Channon K.M. Targeting redox signaling in the vascular wall: from basic science to clinical practice. Curr. Pharm. Des. 2009; 15: 329–342.
 
33.
Walter M.F., Jacob R.F., Bjork R.E., Jeffers B., Buch J., Mizuno Y., Mason R.P. Circulating lipid hydroperoxides predict cardiovascular events in patients with stable coronary artery disease: the PREVENT study. J. Am. Coll. Cardiol. 2008; 51(12 ): 1196–1202.
 
34.
Li G., Chen Y., Hu H., Liu L., Hu X., Wang J., Shi W., Yin D. Association between age-related decline of kidney function and plasma malondiadehyde. Rejuvenation Res. 2012; 15(3): 257–264.
 
35.
Ostalowska A., Koczy B., Słowińska L., Kasperczyk A. Oxidative stress and enzymatic antioxidant status of blood and synovial fluid in rheumatoid arthritis patients. Ann. Acad. Med. Siles. 2016; 70: 196–205.
 
36.
Wiktorowska-Owczarek A., Nowak J.Z. Pathogenesis and prophylaxis of AMD: focus on oxidative stress and antioxidants. Postepy Hig. Med. Dosw. 2010; 64: 333–343.
 
37.
Wang H., Zhao B., Vrcek I., Johnston J.M. Role of Malondialdehyde in the Age-Related Macular Degeneration. In: Oxidative Stress in Applied Basic Research and Clinical Practice. Ed. Sttraton et al. Springer Science + Business Media. LLC 2012, s. 85–93.
 
38.
Ates O., Azizi S., Alp H.H., Kiziltunc A., Beydemir S., Cinici E., Kocer I., Baykal O. Decreased serum paraoxonase 1 activity and increased serum homocysteine and malondialdehyde levels in age-related macular degeneration. Tohoku J. Exp. Med. 2009; 217: 17–22.
 
39.
Gutowicz M. The influence of reactive oxygen species on the central nervous system. Postepy Hig. Med. Dosw. 2011; 65: 104–113.
 
40.
Andersen J.K. Oxidative stress in neurodegeneration: cause or con-sequence? Nat. Med. 2004; 10 Suppl: S18–28.
 
41.
Hensley K., Maidt M.L., Sang H., Markesbery W.R., Floyd R.A. Ele-ctrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J. Neurosci. 1998; 18, 8126–8132.
 
42.
Bulut M., Selek S., Gergerlioglu S., Savas H.A., Yilmaz R.H., Yuce M., Ekici G. Malondialdehyde levels in adult attention-deficit hyperactivity disorder. J. Psychiatry Neurosci. 2007; 32(6): 435–438.
 
43.
MeiLian T., NingNing X., Ming Fang Y., JinFeng Ch., XingChu Y. Effects of sunflower artificial aging on seed vigor and physiological characteristics. Agricultural Sci Tech. 2010; 11(4): 39–43.
 
44.
Pamplona R., Barja G. Mitochorndrial oxidative stress, aging and caloric restriction: the protein and methionine connection. Biochim. Biophys. Acta. 2006; 1757: 496–508.
 
 
CITATIONS (42):
1.
Protective Effects of Sesamol on Systemic Inflammation and Cognitive Impairment in Aging Mice
Bo Ren, Tian Yuan, Xinglin Zhang, Luanfeng Wang, Junru Pan, Yan Liu, Beita Zhao, Weiyang Zhao, Zhigang Liu, Xuebo Liu
Journal of Agricultural and Food Chemistry
 
2.
Evaluation of the effect of thymoquinone in d ‐galactose‐induced memory impairments in rats: Role of MAPK , oxidative stress, and neuroinflammation pathways and telomere length
Zahra Oskouei, Soghra Mehri, Fatemeh Kalalinia, Hossein Hosseinzadeh
Phytotherapy Research
 
3.
Exposure to per- and polyfluoroalkyl substances and premature skin aging
Sayed Mousavi, Juana Delgado-Saborit, Lode Godderis
Journal of Hazardous Materials
 
4.
Cu(II) Complexes with FomA Protein Fragments of Fusobacterium Nucleatum Increase Oxidative Stress and Malondialdehyde Level
Monika Lesiów, Piotr Pietrzyk, Agnieszka Kyzioł, Urszula Komarnicka
Chemical Research in Toxicology
 
5.
Synergistic effects of Ficus Carica extract and extra virgin olive oil against oxidative injury, cytokine liberation, and inflammation mediated by 5-Fluorouracil in cardiac and renal tissues of male albino rats
Mona Elghareeb, Gehad Elshopakey, Basma Hendam, Shaymaa Rezk, Samah Lashen
Environmental Science and Pollution Research
 
6.
Inhibitory Effects of Selenium on Arsenic-Induced Anxiety-/Depression-Like Behavior and Memory Impairment
Noreen Samad, Tazeen Rao, Muhammad Rehman, Sheraz Bhatti, Imran Imran
Biological Trace Element Research
 
7.
Evaluation of the Low Inclusion of Full-Fatted Hermetia illucens Larvae Meal for Layer Chickens: Growth Performance, Nutrient Digestibility, and Gut Health
Xiaohua Chu, Mengmeng Li, Guiying Wang, Kuiming Wang, Rongsheng Shang, Ziyu Wang, Lusheng Li
Frontiers in Veterinary Science
 
8.
Pro-Oxidant Enzymes, Redox Balance and Oxidative Damage to Proteins, Lipids and DNA in Colorectal Cancer Tissue. Is Oxidative Stress Dependent on Tumour Budding and Inflammatory Infiltration?
Justyna Zińczuk, Mateusz Maciejczyk, Konrad Zaręba, Anna Pryczynicz, Violetta Dymicka-Piekarska, Joanna Kamińska, Olga Koper-Lenkiewicz, Joanna Matowicka-Karna, Bogusław Kędra, Anna Zalewska, Katarzyna Guzińska-Ustymowicz
Cancers
 
9.
ROS-mediated lipid peroxidation as a result of Cu(ii) interaction with FomA protein fragments of F. nucleatum: relevance to colorectal carcinogenesis
Monika Lesiów, Urszula Komarnicka, Agnieszka Kyzioł, Alina Bieńko, Piotr Pietrzyk
Metallomics
 
10.
AST/ALT levels, MDA, and liver histopathology of Echinometra mathaei ethanol extract on paracetamol-induced hepatotoxicity in rats
Angelica Kresnamurti, Dita Rakhma, Amitasari Damayanti, Septiyan Santoso, Enggar Restryarto, Wifqi Hadinata, Iwan Hamid
Journal of Basic and Clinical Physiology and Pharmacology
 
11.
Protective effect of gallic acid against arsenic-induced anxiety−/depression- like behaviors and memory impairment in male rats
Noreen Samad, Sadia Jabeen, Imran Imran, Iqra Zulfiqar, Kainat Bilal
Metabolic Brain Disease
 
12.
Effects of Essential Trace Elements and Oxidative Stress on Endemic Arsenism Caused by Coal Burning in PR China
Yong Hu, Tingting Xiao, Qi Wang, Bing Liang, Aihua Zhang
Biological Trace Element Research
 
13.
The PKCδ-Nrf2-ARE signalling pathway may be involved in oxidative stress in arsenic-induced liver damage in rats
Yong Hu, Chun Yu, Maolin Yao, Lei Wang, Bing Liang, Bixia Zhang, Xiaoxin Huang, Aihua Zhang
Environmental Toxicology and Pharmacology
 
14.
Reserpine-induced altered neuro-behavioral, biochemical and histopathological assessments prevent by enhanced antioxidant defence system of thymoquinone in mice
Noreen Samad, Natasha Manzoor, Zahra Muneer, Sheraz Bhatti, Imran Imran
Metabolic Brain Disease
 
15.
Malondialdehyde (MDA) Production in Atherosclerosis Supplemented with Steamed Tomato
Iswari Sri, Muchamad Dafip, Eling Purwantoyo
Pakistan Journal of Biological Sciences
 
16.
Galangin mitigates oxidative stress, inflammation, and apoptosis in a rat model of methotrexate hepatotoxicity
Manal Alfwuaires
Environmental Science and Pollution Research
 
17.
Effects of dietary inclusion of Radix Bupleuri extract on the growth performance, and ultrastructural changes and apoptosis of lung epithelial cells in broilers exposed to atmospheric ammonia
Shiping Bai, Xi Peng, Caimei Wu, Tong Cai, Jiangfeng Liu, Gang Shu
Journal of Animal Science
 
18.
PENGARUH PEMBERIAN JUS BIT TERFORTIFIKASI FESO4 INSTAN (JUS BEEFE) DALAM MENANGGULANGI ANEMIA ATLET REMAJA PUTRI
Mirza Penggalih, Ibtidau Niamilah, Yuga Pramesti, Nia Bactiar, Sheila Wardhani
Jurnal Teknologi dan Industri Pangan
 
19.
Hibiscus sabdariffa in Diabetes Prevention and Treatment—Does It Work? An Evidence-Based Review
Daniel Jamrozik, Weronika Borymska, Ilona Kaczmarczyk-Żebrowska
Foods
 
20.
Effects of Probiotic Supplementation during Pregnancy on the Future Maternal Risk of Metabolic Syndrome
Aleksandra Obuchowska, Kamila Gorczyca, Arkadiusz Standyło, Karolina Obuchowska, Żaneta Kimber-Trojnar, Magdalena Wierzchowska-Opoka, Bożena Leszczyńska-Gorzelak
International Journal of Molecular Sciences
 
21.
Effect of Dried Apple Pomace (DAP) as a Feed Additive on Antioxidant System in the Rumen Fluid
Iga Bartel, Magdalena Koszarska, Kamil Wysocki, Martyna Kozłowska, Małgorzata Szumacher-Strabel, Adam Cieślak, Beata Wyrwał, Aleksandra Szejner, Nina Strzałkowska, Jarosław Horbańczuk, Atanas Atanasov, Artur Jóźwik
International Journal of Molecular Sciences
 
22.
Effects of three feed attractants on the growth performance and meat quality of the largemouth bass (Micropterus salmoides)
Yuhua Yue, Mingshi Chen, Xiaoxue Bao, Yingying Yu, Wei Shi, Suksan Kumkhong, Yuhong Liu, Ying Yang, Hui Yu
Frontiers in Marine Science
 
23.
Effects of Dietary Clostridium butyricum on Carcass Traits, Antioxidant Capacity, Meat Quality, and Fatty Acid Composition of Broilers
Tiantian Yang, Mengsi Du, Xiaobing Wang, Junyong Wang, Jinzhuan Li, Xiaohan Jiang, Rijun Zhang, Dayong Si
Agriculture
 
24.
Oxidative Stress Biomarkers among Schizophrenia Inpatients
Magdalena Więdłocha, Natalia Zborowska, Piotr Marcinowicz, Weronika Dębowska, Marta Dębowska, Anna Zalewska, Mateusz Maciejczyk, Napoleon Waszkiewicz, Agata Szulc
Brain Sciences
 
25.
Sacha inchi albumin delays skin‐aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d‐ galactose induced‐aging mice
Jieyu Zeng, Miaoqing An, Wenni Tian, Kun Wang, Bing Du, Pan Li
Journal of the Science of Food and Agriculture
 
26.
Substituting Fish Meal with Tubiechong (Eupolyphaga sinensis) By-Product in the Diets of Largemouth Bass (Micropterus salmoides): Effects on Growth, Meat Quality, and Liver Health
Yuhua Yue, Binbin Tong, Mingshi Chen, Xiaoxue Bao, Yanming Qiu, Ying Yang, Hui Yu, Yingying Yu, Shouqi Xie
Aquaculture Nutrition
 
27.
Puerarin protects against acetaminophen‐induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway
Wanhai Zhou, Heng He, Qin Wei, Litao Che, Xin Zhao, Wenwen Liu, Yue Yan, Lianqing Hu, Yonghua Du, Zhongqiong Yin, Yongkang Shuai, Li Yang, Ruizhang Feng
Food Science & Nutrition
 
28.
Effects of Tectona grandis L. Extract in Diabetic Rats on Nitric Oxide and Malondialdehyde Levels
Parawansah ., Nuralifah ., Ruslin ., Nurramadhani Sida, Fadhliyah Malik, Atymutmain .
Pakistan Journal of Biological Sciences
 
29.
Study the properties of ram semen preserved at 5°C for different periods after adding different levels of acai fruit extract.
Rad Fadel, Banana Hussien
Bionatura
 
30.
Addition of acai fruit extract to Tris extender and its effect on some parameters of ram semen preserved at cooling.
Radi Fadel, Banana Hussien
Bionatura
 
31.
Physiological response of mussel to rayon microfibers and PCB's exposure: overlooked semi-synthetic micropollutant?
Ningjin Jiang, Xueqing Chang, Wei Huang, Fahim Ullah Khan, James Kar-Hei Fang, Menghong Hu, Elvis Genbo Xu, Youji Wang
Journal of Hazardous Materials
 
32.
Induced Resistance to Control Postharvest Stem-End Rot by Exogenous Methyl Jasmonate in Mango Fruit
Min Li, Xiangxiang Qu, Deqiang Gong, Tianyu Huang, Yu Wang, Yi Yang, Zhaoyin Gao, Zhengke Zhang, Jinhua Sun, Meijiao Hu
 
33.
Metabolomics of Benzene Exposure and Development of Biomarkers for Exposure Hazard Assessment
Hao Li, Qianyu Sun, Fei Li, Boshen Wang, Baoli Zhu
Metabolites
 
34.
The CDPK-related protein kinase HvCRK2 and HvCRK4 interact with HvCML32 to negatively regulate drought tolerance in transgenic Arabidopsis thaliana
Cui Yongmei, Kunlun Wu, Xiaohua Yao
Plant Physiology and Biochemistry
 
35.
Effect of Adding Different Levels of Euterpe oleracea (Açaí) Fruit to the Diet of Laying Hens on the Volume of Ejaculate, Sperm Motility and Some Histological Characteristics
Ola Hussein Abdul Amir, Emad Abdulgabbar Ali
IOP Conference Series: Earth and Environmental Science
 
36.
Biochar-mediated bioremediation: a sustainable strategy to increase Avena sativa L. tolerance to crude oil soil contamination
Riccardo Fedeli, Silvia Celletti, Dmitry Alexandrov, Elvira Nafikova, Stefano Loppi
Environmental Science and Pollution Research
 
37.
OXIDATIVE STRESS BIOMARKERS IN THE CARDIAC AND HEPATIC TISSUES OF RAINBOW TROUT (ONCORHYNCHUS MYKISS WALBAUM) FED THE Β-GLUCAN-SUPPLEMENTED DIET
Halina Tkaczenko, Natalia Kurhaluk, Joanna Grudniewska
The Scientific and Technical Bulletin of the Institute of Animal Science NAAS of Ukraine
 
38.
The importance of oxidative stress in the pathogenesis and treatment of bipolar affective disorder: a review of the literature
Łukasz Łobejko, Michalina Hordejuk, Joanna Róg, Hanna Karakuła-Juchnowicz
Current Problems of Psychiatry
 
39.
Induced resistance to control postharvest stem-end rot by methyl jasmonate in mango fruit
Min Li, Xiangxiang Qu, Deqiang Gong, Tianyu Huang, Yu Wang, Yi Yang, Zhaoyin Gao, Zhengke Zhang, Jinhua Sun, Meijiao Hu
Physiological and Molecular Plant Pathology
 
40.
Nigella sativa oil attenuates inflammation and oxidative stress in experimental myocardial infarction
Raluca Maria Pop, Emilia Vassilopoulou, Mihaela-Elena Jianu, Ștefan Horia Roșian, Marian Taulescu, Mihai Negru, Crina Bercian, Paul-Mihai Boarescu, Ioana Corina Bocsan, Gavriela Feketea, Veronica Sanda Chedea, Francisc Dulf, Jeanine Cruceru, Alina Elena Pârvu, Anca Dana Buzoianu
BMC Complementary Medicine and Therapies
 
41.
Pyrroloquinoline Quinone (PQQ): Exploring its Impact on Human Health and Potential Benefits
Tingdong Yan, Muhammad Farrukh Nisar, Xiaomeng Hu, Jieming Chang, Yichen Wang, Yan Wu, Zhaoguo Liu, Yi Cai, Jia Jia, Yanming Xiao, Chunpeng Wan
Current Research in Food Science
 
42.
Investigation of Determinant Factors for Oxidative Stress Prevention in Leather-shoe Workers Exposed to Benzene
Yuliani Setyaningsih, Bina Kurniawan, Ida Wahyuni, Ekawati, Dina Lusiana Setyowati, M.I. Kartasurya, J.-H. Han, K.-H. Tsai, S. Nursheena, S. Changrob, N. Lisnawati, A.F. Asna, N. Handayani, D.Z. Nuridzin
BIO Web of Conferences
 
eISSN:1734-025X
Journals System - logo
Scroll to top