Dialdehyd malonowy – produkt peroksydacji lipidów jako marker zaburzeń homeostazy i wieku

Beata Całyniuk; Elżbieta Grochowska-Niedworok; Katarzyna Weronika Walkiewicz; Sylwia Kawecka; Ewa Popiołek; Edyta Fatyga

doi:10.18794/aams/65697

2016 vol. 70

Pobierz cytowanie

Dialdehyd malonowy – produkt peroksydacji lipidów jako marker zaburzeń homeostazy i wieku

Beata Całyniuk ¹

Elżbieta Grochowska-Niedworok ¹

Katarzyna Weronika Walkiewicz ²

Sylwia Kawecka ²

Ewa Popiołek ¹

Edyta Fatyga ²

Więcej

Ukryj

Department of Human Nutrition, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland

Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland

Autor do korespondencji

Katarzyna Weronika Walkiewicz

Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland, ul. Piekarska 18, 41-902 Bytom, tel. 32 281 21 22,

Ann. Acad. Med. Siles. 2016;70:224-228

DOI: https://doi.org/10.18794/aams/65697

Artykuł (PDF, 337.43 kB)

Referencje (44) Cytowania (51)

SŁOWA KLUCZOWE

styl życia

wolne rodniki tlenowe

DZIEDZINY

STRESZCZENIE

Dialdehyd malonowy (MDA) w organizmie człowieka pochodzi z dwóch źródeł: spożywanego pokarmu i peroksydacji lipidów występujących w tkankach. Powstawanie MDA, a także wielkość i szybkość utleniania lipidów w tkankach organizmów żywych, zależy od wielu czynników endo- i egzogennych. Produkty peroksydacji lipidów, szczególnie MDA, wykazują właściwości cytotoksyczne, mutagenne i rakotwórcze. Mogą one również hamować enzymy związane z obroną komórki przed stresem oksydacyjnym. Mogą nie tylko przyczyniać się do rozwoju wielu chorób, ale stanowią również część procesu starzenia się. Organizm broni się w pewnym stopniu przed działaniem wolnych rodników, neutralizując je. Głównym źródłem przeciwutleniaczy jest żywność – produkty pochodzenia roślinnego. Styl życia, na który składają się dieta i aktywność fizyczna, jest ważnym elementem w zachowaniu zdrowia rozumianego jako dobre samopoczucie fizyczne i psychiczne. Nawyki żywieniowe i dieta bogata w przeciwutleniacze są modyfikowalnymi czynnikami, które nie tylko zapobiegają chorobom związanym z wiekiem, ale także opóźniają procesy starzenia.

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