Dialdehyd malonowy – produkt peroksydacji lipidów jako marker zaburzeń homeostazy i wieku
 
Więcej
Ukryj
1
Department of Human Nutrition, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland
 
2
Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland
 
 
Autor do korespondencji
Katarzyna Weronika Walkiewicz   

Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia in Katowice, Poland, ul. Piekarska 18, 41-902 Bytom, tel. 32 281 21 22,
 
 
Ann. Acad. Med. Siles. 2016;70:224-228
 
SŁOWA KLUCZOWE
DZIEDZINY
STRESZCZENIE
Dialdehyd malonowy (MDA) w organizmie człowieka pochodzi z dwóch źródeł: spożywanego pokarmu i peroksydacji lipidów występujących w tkankach. Powstawanie MDA, a także wielkość i szybkość utleniania lipidów w tkankach organizmów żywych, zależy od wielu czynników endo- i egzogennych. Produkty peroksydacji lipidów, szczególnie MDA, wykazują właściwości cytotoksyczne, mutagenne i rakotwórcze. Mogą one również hamować enzymy związane z obroną komórki przed stresem oksydacyjnym. Mogą nie tylko przyczyniać się do rozwoju wielu chorób, ale stanowią również część procesu starzenia się. Organizm broni się w pewnym stopniu przed działaniem wolnych rodników, neutralizując je. Głównym źródłem przeciwutleniaczy jest żywność – produkty pochodzenia roślinnego. Styl życia, na który składają się dieta i aktywność fizyczna, jest ważnym elementem w zachowaniu zdrowia rozumianego jako dobre samopoczucie fizyczne i psychiczne. Nawyki żywieniowe i dieta bogata w przeciwutleniacze są modyfikowalnymi czynnikami, które nie tylko zapobiegają chorobom związanym z wiekiem, ale także opóźniają procesy starzenia.
 
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