PL EN
 
2016 vol. 70
Get citation
Sentinel lymph node (SLN) identification in breast cancer patients, using SentiMag® ferromagnetic method. Assessment of usefulness and limitations in group of our own patients
,
 
,
 
,
 
 
 
 
More details
Hide details
1
Klinika Chirurgii Onkologicznej, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Śląski Uniwersytet Medyczny w Katowicach
2
Klinika Onkologii Klinicznej, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Śląski Uniwersytet Medyczny w Katowicach
3
Katedra i Klinika Chirurgii Ogólnej, Naczyniowej i Transplantacyjnej, Wydział Lekarski w Katowicach, Śląski Uniwersytet Medyczny w Katowicach
CORRESPONDING AUTHOR
Andrzej Lorek   

Klinika Chirurgii Onkologicznej, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Śląski Uniwersytet Medyczny w Katowicach, ul. Ceglana 35, 40-514 Katowice, tel. +48 32 358 13 15
 
Ann. Acad. Med. Siles. 2016;70:236–241
DOI: https://doi.org/10.18794/aams/66764
 
 
Article (PDF)
References (20)
 
KEYWORDS
Sentinel lymph node biopsy
breast cancer
superparamagnetic particles of iron oxide
breast density according to the American College of Radiology (ACR)
 
TOPICS
Surgery
Oncology
 
ABSTRACT
Objective:
The paper aims to assess SLN signal intensity, depending on: breast density according to ACR (American College of Radiology), age, the presence of scars and the time from tracer administration.

Material and methods:
The study encompassed 161 SLN biopsies. The study group included 14 patients with scars.

Results:
Analysing the influence of ACR-based breast density and the time from tracer administration on the SLN signal intensity, a statistically positive correlation was found between signal intensity and the time from tracer administration in patients with ACR levels 1 and 2. In the ACR level 3 and 4 groups, no significant correlation was found. SLN signal intensity in relation to the patients’ age indicated a statistically significant negative correlation of SLN signal intensity in the entire group and in ACR 1. The analysis of 14 patients with scars demonstrated a statistically significant lower SLN signal intensity.

Conclusions:
It was found that the time from Sienna+® administration affects SLN signal intensity in relation to ACR-based breast density types 1 and 2. No such correlation was observed in density types 3 and 4. Elderly patients, especially with ACR-based breast density types 1 and 2, are more likely to present lower values of SLN impulses. Patients who had earlier surgical interventions within the upper external quadrants are more likely to present lower values of SLN impulses.

 
REFERENCES (20)
1.
Schwartz G., Giuliano A., Veronesi U. Preceedings of the consensus conference on the role of sentinel lymph node biopsy in carcinoma of the breast, April 19–22, 2001, Philadelphia, Pennsylvania. Cancer 2002; 94: 2542–2551.
Google Scholar
 
 
2.
Douek M., Klaase J., Monypenny I., Kothari A., Zechmeister K., Brown D., Wyld L., Drew P., Garmo H., Agbaje O., Pankhurst Q., Anninga B., Grootendorst M., Ten Haken B., Hall-Craggs M.A., Purushotham A., Pinder S. Sentinel node biopsy using a magnetic tracer versus standard technique: the SentiMAG Multicentre Trial. Ann. Surg. Oncol. 2014; 21(4): 1237–1245.
Google Scholar
 
 
3.
Thill M., Kurylcio A., Welter R., van Haasteren V., Grosse B., Berclaz G., Polkowski W., Hauser N. Response to Barranger E., Ihrai T., response to the article by Thill et al.: "The Central-European SentiMagstudy: Sentinel lymph node biopsy with supermagnetic iron oxide (SPIO) vs. radioisotope". The Breast 2014; 23(2): 175–179. Breast 2014; 23(5): 692.
Google Scholar
 
 
4.
Rubio I.T., Diaz-Botero S., Esgueva A., Rodriguez R., Cortadellas T., Cordoba O., Espinosa-Bravo M. The superparamagnetic iron oxide is equivalent to the Tc99 radiotracer method for identifying the sentinel lymph node in breast cancer. Eur. J. Surg. Oncol. 2015; 41(1): 46–51.
Google Scholar
 
 
5.
Piñero-Madrona A., Torró-Richart J.A., de León-Carrillo J.M., de Castro-Parga G., Navarro-Cecilia J., Domínguez-Cunchillos F., Román-San-tamaría J.M., Fuster-Diana C., Pardo-García R. Superparamagnetic iron oxide as a tracer for sentinel node biopsy in breast cancer: a comparative non-inferiority study. Eur. J. Surg. Oncol. 2015; 41(8): 991–997.
Google Scholar
 
 
6.
Pouw J.J., Grootendorst M.R., Bezooijen R., Klazen CA., De Bruin W.I., Klaase J.M., Hall-Craggs M.A., Douek M., Ten Haken B. Pre-operative sentinel lymph node localization in breast cancer with superparamagnetic iron oxide MRI: the SentiMAG Multicentre Trial imaging subprotocol. Br. J. Radiol. 2015; 88(1056): 20150634.
Google Scholar
 
 
7.
Ghilli M., MD Carretta E., Di Filippo F., Battaglia C., Fustaino L., Galanou I., Di Filippo S., Rucci P., Fantini M.P., Roncella M. The super-paramagnetic iron oxide tracer: a valid alternative in sentinel node biopsy for breast cancer treatment. Eur. J. Cancer Care 2015; Sep 14: DOI: 10.1111/ecc.12385.
CrossRef
 
Google Scholar
 
 
8.
Tafra L., Lannin D.R., Swanson M.S., Van Eyk J.J., Verbanac K.M., Chua A.N., Ng P.C., Edwards M.S., Halliday B.E., Henry C.A., Sommers L.M., Carman C.M., Molin M.R., Yurko J.E., Perry R.R., Williams R. Multicenter trial of sentinel node biopsy for breast cancer using both technetium sulfur colloid and isosulfan blue dye. Ann. Surg. 2001; 233: 51–59.
Google Scholar
 
 
9.
Cox C.E., Dupont E., Whitehead G.F., Ebert M.D., Nguyen K., Peltz E.S., Peckham D., Cantor A. Age and body mass index may increase the chance of failure in sentinel lymph node biopsy for women with breast cancer. Breast J. 2002; 8(2): 88–91.
Google Scholar
 
 
10.
Haut J., Jacob D., Laurent E., Rubinstein M., Rahier L. Preoperative localisation and analysis (preoperative and definitive) of the sentinel node in clinical and subclinical breast carcinoma. Presented at the Second International Sentinel Node Congress, December 1–4. Santa Monica 2000 (Abstract Book p. 54).
Google Scholar
 
 
11.
Hughes M., Goffman T.G., Perry R.R., Laronga C. Obesity and lymphatic mapping with sentinel lymph node biopsy in breast cancer. Am. J. Surg. 2004; 187(1): 52–57.
Google Scholar
 
 
12.
Sutton R., Kollias J., Prasad V., Chatterton B., Grantley Gill P. Sameday lymphoscintigraphy and sentinel node biopsy for early breast cancer. ANZ J. Surg. 2002; 72(8): 542–546.
Google Scholar
 
 
13.
Bergkvist L., Frisell J., Liljegren G., Celebioglu F., Damm S., Thörn M. Multicentre study of detection and false-negative rates in sentinel node biopsy for breast cancer. Br. J. Surg. 2001; 88(12): 1644–1648.
Google Scholar
 
 
14.
Lamichhane N., Shen K.W., Li C.L., Han Q.X., Zhang Y.J., Shao Z.M. Sentinel lymph node biopsy in breast cancer patients after overnight migration of radiolabelled sulphur colloid. Postgrad. Med. J. 2004; 80: 546–550.
Google Scholar
 
 
15.
Schirrmeister H., Kotzerke J., Vogl F., Buck A., Czech N., Koretz K., Helm G., Kreienberg R., Kühn T. Prospective evaluation of factors influencing success rates of sentinel node biopsy in 814 breast cancer patients. Cancer Biother. Radiopharm. 2004; 19: 784–790.
Google Scholar
 
 
16.
Yararbas U., Argon A.M., Yeniay L., Kapkac M. Problematic aspects of sentinel lymph node biopsy and its relation to previous excisional biopsy in breast cancer. Clin. Nucl. Med. 2009; 34(12): 854–858.
Google Scholar
 
 
17.
Tafra L., Lannin D.R., Swanson M.S., Van Eyk J.J., Verbanac K.M., Chua A.N., Ng P.C., Edwards M.S., Halliday B.E., Henry C.A., Sommers L.M., Carman C.M., Molin M.R., Yurko J.E., Perry R.R., Williams R. Multicenter trial of sentinel node biopsy for breast cancer usunig both technetium sulfur colloid and isosulfan blue dye. Ann. Surg. 2001; 233: 51–59.
Google Scholar
 
 
18.
Luini A., Galimberti V., Gatti G., Arnone P., Vento A.R., Trifirò G., Viale G., Rotmensz N., Fernandez J.R., Gilardi D., Paganelli G. The sentinel node biopsy after previous breast surgery: preliminary results on 543 patients treated at the European Institute of Oncology. Breast Cancer Res. Treat. 2005; 89: 159–163.
Google Scholar
 
 
19.
Celebioglu F., Frisell J., Danielsson R., Bergkvist L. Sentinel node biopsy in non-palpable breast cancer and in patients with a previous diagnostic excision. Eur. J. Surg. Oncol. 2007; 33: 276–280.
Google Scholar
 
 
20.
Haigh P.I., Hansen N.M., Qi K., Giuliano A.E. Biopsy method and excision volume do not affect success rate of subsequent sentinel lymph node dissection in breast cancer. Ann. Surg. Oncol. 2000; 7: 21–27.
Google Scholar
 
 
Share
Send by email
RELATED ARTICLE
Serum levels of VEGF-A, sVEGFR-2 and galectin-3 do not correlate with clinical stage, tumor size, or effectiveness of perioperative chemotherapy in patients with non-metastatic breast cancer
The news about the infl uence of melatonin on pathogenesis and therapy of breast cancer
Neuroendocrine carcinoma of the mammary gland. A case report of synchronous occurrence of two different carcinomas in one breast
The analysis of breast cancer and colorectal cancer incidence in Silesian province based on available data on malignancies – National Cancer Registry and National Health Fund
Indexes
 
Keywords index
Topics index
Authors index
eISSN:1734-025X


© 2006-2023 Journal hosting platform by Bentus