Electrolyte equilibrium disorders in patients with metabolic syndrome
More details
Hide details
Klinika Chorób Wewnętrznych i Metabolicznych Śląskiego Uniwersytetu Medycznego w Katowicach
Ann. Acad. Med. Siles. 2010;64:36-42
The role of magnesium defi ciency in metabolic syndrome pathophysiology is one of the issue presently discussed in the literature. The others electrolyte disturbances in this syndrome are also the object of interest. The aim of the study was to analyze electrolyte equilibrium disorders in patients with metabolic syndrome.

Material and Methods:
The study group consisted of 36 (29 females and 9 males) patients with metabolic syndrome hospitalized in the Internal Medicine Wards of District Hospitals in Blachownia and Pajęczno and 29 (10 females and 19 males) healthy volunteers (control group). The metabolic syndrome was diagnosed according to IDF (2005) criteria.

In contrast to the sodium and potassium serum magnesium level was signifi cantly lower in patients with metabolic syndrome than in the control group. Moreover there was a negative serum magnesium correlation between waist circumference and body mass index among patients with metabolic syndrome. There were positive correlations between serum sodium and systolic and diastolic blood pressure, serum potassium and triglycerides concentrations in the group with metabolic syndrome. The foregoing correlations were not found in the control group.

1. Serum magnesium was significantly lower in patients with metabolic syndrome than in the control group. 2. The correlation between serum magnesium and waist circumference, body mass index shows the possible abdominal fatty tissue influence on magnesium equilibrium among patients with metabolic syndrome. 3. The positive correlation between serum sodium and systolic and diastolic blood pressure points the possible role of sodium in pathogenesis of hypertension in metabolic syndrome.

Corica F., Corsonello A., Ientile R. i wsp. “Serum Ionized Magnesium Levels in Relation to Metabolic Syndrome in Type 2’’,Diabetic Patients. J. Am. Coll. Nutr. 2006 Jun;25(3):210-5.
Hordyjewska A., Pasternak K. Magnesium role in cardiovascular diseases’’. Ann Univ Mariae Curie Sklodowska [Med]. 2004;59(2):108-13.
Lima Mde L., Cruz T., Rodrigues L.E. i wsp. Serum and intracellular magnesium defi ciency in patients with metabolic syndrome-- evidences for its relation to insulin resistance. Diabetes Res. Clin. Pract. 2009 Feb;83(2):257-62.
V. Topalov, D. Kovacević, A. Topalov, D. Kovacević Magnesium in cardiology Medicinski pregled. 53(5-6):319-24.
Strazzullo P., Barbato A., Galletti F. i wsp. Abnormalities of renal sodium handling in the metabolic syndrome. Results of the Olivetti Heart Study. J Hypertens. 2006 Aug;24(8):1633-9.
Hoff mann I.S., Cubeddu L.X. Salt and the metabolic syndrome. Nutr. Metab. Cardiovasc. Dis. 2009 Feb;19(2):123-8.
Guerrero-Romero F., Rodriguez-Moran M., Low serum magnesium levels and metabolic syndrome. Diabetes. Res. Rev. 2006 Nov-Dec; 22(6):47 1-6.
Bruno Sontia and Rhian M. Touyz Role of magnesium in hypertension Archives of Biochemistry and Biophysics Volume 458, Issue 1, 1 February 2007, 33-39.
Michon P. Level of total and ionized magnesium fraction based on biochemical analysis of blood and hair and eff ect of supplemented magnesium (Slow Mag B6) on selected parameters in hypertension of patients treated with various groups of drugs. Ann. Acad. Med. Stetin. 2002;48:85- 97.
Głowania A. Przyczyny i konsekwencje niedoboru magnezu u osób chorych na cukrzycę. Medycyna Metaboliczna 2000, tom IV, Nr 4: 48-54.
Journals System - logo
Scroll to top