SŁOWA KLUCZOWE
DZIEDZINY
STRESZCZENIE
Padaczka lekooporna (drug-resistant epilepsy – DRE) u dzieci jest jedną z najczęściej diagnozowanych chorób układu nerwowego. Pomimo dostępności farmakoterapii o różnych mechanizmach działania lekooporność determinuje brak możliwości osiągnięcia zamierzonego efektu terapeutycznego. Mając na uwadze złożoną etiologię omawianej jednostki chorobowej, istnieje pilna potrzeba zgłębiania wiedzy w zakresie determinantów DRE, jak i możliwości poprawy jakości życia pacjentów oraz ich rodzin. Praca stanowi opis z podsumowaniem najnowszych osiągnięć i aktualnego stanu wiedzy odnoszącego się do charakterystyki klinicznej, epidemiologii, możliwych powikłań, a szczególnie podłoża genetycznego DRE w polskiej populacji dzieci.
 
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